• Tear damage starts at double (+100%) and decreases over range to roughly (+30%). * item room, treasure room, item room pool, raccoon, green. UNLOCK: Unlock this item by beating the Dark Room with Azazel. *, metal, grey, gray, silver, pill, cross. 'Bad Trip' Upon taking damage, Isaac leaves a trail of red creep that damages enemies until he leaves the room. Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost'. After a • Gives Isaac a full mapping effect, revealing the entire floor and locations of all secret rooms. • Gives Isaac a large white halo around him, that deals a bit of damage to any enemies in contact with the ring. Binding of Isaac Pay to Play cheat sheet with detailed descriptions, quote, and IDs. • An orbiting fly which deals 2 contact damage per tick to enemies. satanic, star, red, black. UNLOCK: Unlock this item by donating 10 pennies to the Shop. • Allows you to loop through the final floor infinitely. • After blocking a tear, this orbital has a chance to drop an eternal heart. * , the lost item pool, cross, yellow, golden, glow. Use the search boxes below to find out which items from The Binding of Isaac synergize! • The Hive Mind item will cause Rotten Baby's flies to deal double damage. Item Pool: Item Room, Super Sloth Miniboss, Bomb Beggar, * boss rush pool, boss rush room, item room, treasure room, item room pool, bob sloth, If it does, it will drop a random trinket, coin, heart and key, • The Walnut trinket is destroyed once the effect activates, • Causes any orbitals you have to stop moving while held, • Stops shooting familiars from moving (including Lilith's Incubus), • Some familiars with irregular movement are not affected by Duct Tape, such as Abel, BBF, Bumbo, Guppy's Hair Ball, Lil Gurdy, Punching Bag, Robo-Baby 2.0, Succubus, *, grey, gray, tp, toilet, paper, roll, silver, • While held, shops will now appear on the womb floors (The Womb, Utero and Scarred Womb). purple. • Fully restores all red heart containers. • The knife can also do damage without being thrown as a close range melee weapon. • If you have no coins, it gives you two. UNLOCK: Unlock this item by beating Mom's Heart on Hard Mode with Apollyon. UNLOCK: Unlock this item by beating Isaac in the Cathedral 5 times. • For the Lost and Keeper characters, this item simply gives a permanent Tears Up. item room, treasure room, item room pool, dungeon room, blood challenge • Takes three hits to deplete and can be refilled with red hearts, but disappears forever when depleted. • When used this card will activate a use of your spacebar item for free. • The laser ring does damage equal to your normal tears rapidly to any enemies inside the ring. • Drops a large bomb below the player which does 110 damage. • A spacebar item that fires 8 of Isaac's tears in a circle around him. • While held, you heal for half a red heart every time you use a key to open a door or golden chest. • Breaks the normal fire rate cap, allowing you to fire faster than the normal maximum. Reddit: The Binding of Isaac r/ bindingofisaac. • Any further cubes of meat past 4 will start the cycle again. * boss room pool, boss room item, item room, treasure room, item room pool, black, baby, white, eyes. period of time. * devil pool, devil room pool, devil deal, item room, treasure room, item room pool. the chain is fully extended. • The daze effect is effectively permanent for normal enemies, and has a much longer duration for bosses compared to other status effects, • The visual effect of a Glaucoma tear is hard to notice, however it is slightly lighter than normal tears and is not a perfect circle shape, • This item gives you a chance that instead of firing tears you will fire an egg sack, which slows enemies on hit and drops a pool of white slowing creep below them, • If a parasitoid shot successfully hits an enemy, a blue friendly fly or spider is spawned, • Causes your tears to become piercing, allowing them to travel through enemies, • After hitting its first enemy, each tear will double in damage and gain a homing effect. Based on the Steam Workshop mod (originally called Hungry Tears) created by Echo. • When used, this item will spawn a bone orbital or charmed Bony for each enemy killed in the current room. • Isaac's touch now petrifies enemies, turning them to gold for a few seconds. room pool, yellow, red, blue, medicine, jar, drug. * normal beggar pool, normal judgement pool, coin beggar pool, coin judgement pool, shop room pool, • As soon as Isaac has half a red heart or more, this item deactivates. The Binding of Isaac: Afterbirth+ is a randomly generated action-shooter with heavy RPG and rogue-like elements. UNLOCK: Unlock this item by collecting 3 Guppy items and transforming into Guppy. poop, pots, TNT, red poop, stone blocks etc.). with enemies and the beams deal damage equal to your tear damage + 20. from the pool. • While at 1/2 of a red heart, it will begin to remove your soul hearts and black hearts on damage again. • Gives Isaac high damage tears with a short range. * astrology, astronomy, item room, treasure room, item room pool, black, blue, cyan, glow. • When used, the Mega Bean will freeze all enemies in the current room for a couple of seconds, deal 5 damage and poison any enemies in close proximity and send a wave of spikes across the room in the direction you are facing. Each tick of poison damage is equal to your normal tear damage, • Some random tears will gain the Rubber Cement effect and become bouncy, • Grants +0.25 Speed, +0.75 Range, +0.1 Shot Speed, +0.2 Tears, +0.5 Damage and +1 Luck when Isaac's active item is fully charged, • Infinite use items such as Potato Peeler count as charged and provide the bonus from this trinket, • Grants +0.5 Speed, +1.5 Range, +0.3 Shot Speed, +0.4 Tears, +1.5 Damage when Isaac's active item is completely uncharged. • Isaac can now pick up hearts while at full health, which will UNLOCK: Unlock this item by beating the Caves 30 times and defeating C.H.A.D. judgement pool, boss room pool, boss room item, the lost item pool, carton, fly, flies, milk, * dungeon room, blood challenge room, arena pool, • When used, drops a pool of 'lemonade' on the floor which • Getting a third Ball of Bandages will transform the head into bandage girl which will chase enemies dealing 3.5 contact damage per tick while firing charm tears. • Very similar to the My Little Unicorn item but does not deal contact damage. • An item that often appears in the shop. • Gives Isaac an eternal heart when used. • Can drop any kind of heart, coin, bomb or key. • When used, farts on nearby enemies and knocks them backwards away from Isaac. • -35% Damage Down (0.65 damage multiplier). • Higher chance of a Devil Deal opening after the boss fight (Approximately +20% through testing). • As you hold down the fire button, shots will float in the same place until you release the fire key again. • A one time use active item that when used, will spawn 2 random item pedestals from the item pool associated with the current room (e.g. * boss room pool, boss room item, grey, gray, whip. * item room, treasure room, item room pool, purple. • Can be combined with Midas Touch to turn enemies into Golden Poop. • Gives Isaac an invincibility shield for a few seconds when hit down to 1/2 heart remaining. Blue Baby, The Lost). Item Pool: Gold Chest, Greed Mode Gold Chest, Dead shopkeeper. normal beggar pool, normal judgement pool, coin beggar pool, coin • If used during the Satan fight, The Bible will instantly kill Isaac. * boss rush pool, boss rush room, shop room pool, shop item pool, item room, treasure room, UNLOCK: Unlock this item by beating the Chest with Eve. * item room, treasure room, item room pool, red, bloody, eyeball. • Isaac's normal bombs become pink and causes them to drop random pickups when they explode (e.g. • Resurrection takes place before all other items which give you an extra life, except Guppy's Collar. UNLOCK: Unlock this item by beating Challenge #16 (Computer Savvy). beggar pool, coin judgement pool, shop room pool, shop item pool, bag, • When playing as the Keeper, this item drops 0-1 coins instead. • When killing an enemy, you have a very small chance to gain the ability to fly for the rest of the room. room, treasure room, item room pool, celebrate good times come on, the • Tears become flat and disc shaped giving them a larger hitbox. pinned by moderators. • The Boomerang can be used to kill shopkeeper corpses, allowing you to farm their drops for coins, items, Steam Sale etc. UNLOCK: Unlock this item by beating Boss Rush with Lazarus. • When you die with this item, you respawn in the same room with 1 heart and the Anemic item. The following will NOT count as picking up items and therefore doesn't add entries to the collection grid: Any item interaction during seeded runs. share . red, pink, broken. UNLOCK: Unlock this item by beating challenge #23 (Blue Bomber). • A familiar which follows Isaac and drops half a red heart every 3 rooms. Vote . • +50% / 1.5 times Damage Multiplier (Does not stack with the Magic Mushroom multiplier). red, pink, broken. Item Pool: Angel Room, Greed Mode Angel Room. • Every time this item deals damage to an enemy, it has a chance to drop 1/2 red hearts or 1/2 soul hearts. • Allows you to fire a red flame infront of you, similar to the random: Item room, Secret room, Super secret room, the I AM ERROR room * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, dead, baby, • Black Judas has a damage multiplier of 2.00 (double Isaac's damage) and an additional +0.1 Speed. • Synergizes well with some tear modifiers such as Ipecac, which causes it to do massive damage. • Displays a random cryptic message on the screen similar to the fortune machine ones. UNLOCK: Unlock this item by beating Ultra Pride. * headless horseman, headless horsemen, red, grey, gray. • Gives Isaac a familiar golden Censer which creates a huge aura of light that slows down any enemies inside it. • If a needle hits a non-boss enemy it will instantly kill it and will explode into a circle of 10 more needles, • The 10 spawned needles will also deal 3 times your tear damage, but won't instantly kill enemies or explode into more needles, • The chance to for each tear to become a needle is affected by your luck stat and at +15 Luck it will activate every time. • Takes three hits to deplete and can be refilled with red hearts, but disappears forever when depleted. • A random chance when you take damage to get an invincibility * item room, treasure room, item room pool, dice pip, red. damage up at any range for tears. * golden chest pool, gold chest pool, item room, treasure room, item room pool, green, ball, *, the lost item pool, silver, metal, grey, gray. item room pool, red, boom, tnt, * item room, treasure room, item room pool, wooden, cross, brown, • Isaac can now hold two trinkets at the same time, • Allows you to pick up more trinkets while also holding The Tick, * shop room pool, shop item pool, purple, pink, bag. card. • Causes your friendly blue spiders and flies to become bigger and do 2x more damage. • Damage dealt is equal to your tear damage * 2. UNLOCK: Unlock this item by beating Mom's Heart 7 times. • If you also have Lost Contact, tears will bounce off enemy projectiles instead of being destroyed. • A familiar the follows Isaac and fires random tears. * item room, treasure room, item room pool, dry baby is best baby, northernlion, fat skeleton, UNLOCK: Unlock this item by defeating The Lamb in under 20 minutes. UNLOCK: Unlock this item by beating the Isaac boss with Eden. • If the spacebar is held for too long (about 1 second) when it has no charge, you will take damage. satanic, star, red, black. After picking up a coin he has a random chance to drop * item room, treasure room, item room poolgrey, gray. • Deals 40 damage to everything in the room when used. • This is one of the items which allows you to transform into Guppy. * item room, treasure room, item room pool, red. Based on the Steam Workshop mod created by Ratlah. * item room, treasure room, item room pool, black, grey, gray, extra life, egypt, grey, gray. lightning, bolt. UNLOCK: Unlock this item by beating Satan with Isaac. • Increases the size of your player sprite, but doesn't increase the hitbox. white, grey, gray. • Has a chance to drop from the Super Lust miniboss fight. After a few seconds, the crosshair will disappear, and the Ghost will do certain things based on what you targeted: • Items, pickups, trinkets: Brings them to Isaac. UNLOCK: Unlock this item by beating the Boss Rush with Azazel. • When used, rerolls each item you currently own into another • If used in the Boss Rush, all the duplicates can be taken for free as well as one of the original items. *, orange, brown, yellow, gold, coin, cent, • Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health. • If the spacebar is held for too long (about 1 second) when it has no charge, you will take damage. • The poison effect leaves a damage over time, which deals 4 or 6 damage per tick. rooms have been removed from those floors. • Allows you to create one brown tunnel and one blue tunnel in the floor, that can be used to teleport between wherever you placed each one. • A one-time use item which when used, will duplicate any pedestal items or consumables in the current room. • Tears now have a random chance to apply a shrinking effect, causing enemies to shrink in size and also run away from Isaac. * angel room pool, god room pool, angel room item, shop room pool, shop item pool, • This card is useless for the Bluе Baby. * boss room pool, boss room item, sticks, brown, yellow, * angel room pool, god room pool, angel room item, the lost item pool, cup, wooden, gold, • The Blank Card can also be used to mimic mystic runes as well as tarot cards. In Afterbirth this item gives +17.5% devil deal chance instead of +25%, * library pool, library room, book room pool, item room, treasure room, item room pool, • The above stats only apply to tears fired from Isaac's left eye * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, • When used, fires a high damage laser in a straight line across the room in a similar way to Brimstone. * item room, treasure room, item room pool, grey, gray, magnet. arrow. • Tears shrink and grow in size as they go across the room. UNLOCK: Unlock this item by beating Mom's heart 2 times. • Taking the Goat Head (or any other item) in a Devil Deal bars you from encountering Angel Rooms naturally. Happens a total of 3 times over 30 seconds, • ??? In Afterbirth this orbital can now block shots, making it equal to the Cube of Meat. Can be used with Placebo to generate infinite batteries, • Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). golden, yellow, glow. • • Black Bean deals 26 damage total (5 initially then 21 in a Damage over Time effect. casting the effect of Crack The Sky. judgement pool, boss room pool, boss room item, the lost item pool, green, bone, lump, yellow, * boss room pool, boss room item, brown, leather, bag, sack, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, panties, UNLOCK: Unlock this item by beating the Isaac boss with Eden. • Increases the chance of champion enemies appearing. • It will mimic any tear effects you currently have and also copy your current stats, meaning it will fire with the same damage, fire rate and range. • When Isaac takes damage, a white attack fly will spawn that orbits him at a similar distance to the Distant Admiration fly. Contagion "Outbreak! 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